Lactic vs. Glycolic Acid: Which Exfoliant Actually Works for Sensitive Skin in 2025?

Confused Between Lactic and Glycolic Acid? One Works — The Other Wrecks Sensitive Skin

If you’ve got sensitive skin, choosing the wrong exfoliant isn’t just ineffective — it’s a fast track to irritation, redness, and flare-ups.

Google’s flooded with generic skincare lists. What you need is a clinical breakdown: What works, what backfires, and what derms actually recommend for sensitive, reactive, or redness-prone skin in 2025.

We’ll settle the Lactic vs Glycolic debate — with real-world data, product picks, and a usage routine that won’t destroy your barrier.

TL;DR: Which One Wins?

🏆 Lactic Acid is better for sensitive skin.
It’s larger in molecule size, penetrates more slowly, and is clinically proven to be less irritating.
Glycolic is faster — but harsher. Sensitive skin? Don’t risk it.

What’s the Difference Between Lactic and Glycolic Acid?

Feature Lactic Acid Glycolic Acid
Molecule Size Larger Smaller
Penetration Speed Slower (gentler) Faster (more aggressive)
Best For Sensitive skin, dryness, dullness Oily skin, acne scars, thickened texture
Hydration Acts as a humectant Can be drying
Irritation Risk Low High, especially on thin or reactive skin
Ideal % for Home Use 5%–10% 5%–7% (any higher = pro-level)

Who Should Use Lactic Acid?

✅ Use Lactic Acid if you:

  • Have sensitive, dry, or easily irritated skin

  • Experience redness, tightness, or flaking with other acids

  • Want gentle brightening and hydration, not a chemical peel

Lactic is an AHA that exfoliates without compromising your barrier — and it draws water into the skin, unlike Glycolic.

Who Should Use Glycolic Acid?

⚠️ Use Glycolic Acid only if you:

  • Have oily, thick, or acne-prone skin

  • Already tolerate actives like retinol or vitamin C

  • Want fast resurfacing — and don’t mind a little sting

Glycolic is more aggressive, and while powerful, it’s often too much for sensitive skin — especially around the cheeks or under-eye area.

Red-Approved Products (2025)

🧴 Best Lactic Acid for Sensitive Skin:

The Ordinary Lactic Acid 5% + HA

  • Ultra-affordable, beginner-friendly

  • Bonus: Hyaluronic Acid for hydration

  • Use 2–3x/week after cleansing
    [Affiliate link or product CTA]

Naturium Lactic Acid 10% Resurfacing Serum

  • Stronger but buffered

  • Good for building tolerance slowly
    [View full review]

 Glycolic Acids (Use With Caution if Sensitive):

Paula’s Choice 8% AHA Gel Exfoliant

  • Very effective — but start slow

  • Not recommended for rosacea or barrier issues
    [See usage precautions]

The Ordinary Glycolic Acid 7% Toning Solution

  • cult classic — but many react to it
    [Is it too harsh for you?]

How to Use Acids Safely on Sensitive Skin

  1. Apply only at night

  2. Start with once a week, then build to 2–3x/week

  3. Always apply to dry skin (wet skin = more absorption = more irritation)

  4. Follow with ceramide-rich moisturizer

  5. SPF 50 every single morning — no exceptions

What to Never Mix With Lactic or Glycolic Acid

  • ❌ Vitamin C (can destabilize pH)

  • ❌ Retinoids (alternate nights only)

  • ❌ Physical scrubs (damages barrier)

  • ❌ Fragrance-heavy toners or actives

Lactic Acid Wins for Sensitive Skin in 2025

Glycolic is strong — but it’s a blunt instrument.
Lactic Acid gives you results without wrecking your skin barrier.

If you’re:

  • Dealing with dry patches, tightness, or post-acne redness…

  • Struggling with actives burning your skin…

  • Tired of products making things worse…

Then Lactic Acid is your best move.

Next Step: Find Your Acid Match

Take the 30-Second Acid Quiz
→ Discover the exact exfoliant based on your skin tone, sensitivity, and pigmentation type.

🎯 30-Second Acid Match Quiz






William Reid
A science writer through and through, William Reid’s first starting working on offline local newspapers. An obsessive fascination with all things science/health blossomed from a hobby into a career. Before hopping over to Optic Flux, William worked as a freelancer for many online tech publications including ScienceWorld, JoyStiq and Digg. William serves as our lead science and health reporter.